Apple’s MacBook Neo laptop is compatible with current Line 6 products, and software. Just like other Apple Silicon systems, the Apple A18 Pro chip is in the same category. Line 6 software is supported by the current macOS version.
You can find more detailed info on this page:
https://kb.line6.com/macos12-monterey-macos13-ventura-silicon-m1-m2-chip-compatibility